Gene Editing Core Services

Introduction

Gene editing techniques are not only indispensable for a wide range of gene therapy applications and clinical trials but also crucial for numerous research applications in fields such as functional genomics, disease modeling, and drug discovery. As gene therapies based on these cutting-edge techniques are expected to become a mainstream form of treatment in the next 3-5 years, the demand for gene editing in research applications is also steadily increasing.

To fill this gap, the gene editing core at Children’s National offers cutting-edge gene editing services for users at Children’s National Medical Center, the DMV region, and across the nation. We are committed to assisting with CRISPR screens and the generation of gene-edited cell lines and organisms in a timely and cost-effective manner. Our core aims to facilitate the identification and validation of innovative therapeutic targets, expedite translational research, and propel the advancement of precision medicine for the benefit of patients and the scientific community.

Services

We offer the following services (and may subject to change):

  • Pooled CRISPR screens (full or partial services include library design, construction, lentivirus packaging, screen, bioinformatics analysis);
  • CRISPR + single-cell readouts (e.g., Perturb-seq);
  • Gene knockout in various cell types;
  • Consultation, proposal writing support;
  • Other custom gene editing tasks

Price chart and contact information

*Internal: Children’s National users; External: other universities or non-profit research organizations; Industry: industrial users

For price list and further information, please contact Dr. Wei Li (wli2 AT childrensnational.org) or Dr. Lumen Chao (lchao AT childrensnational.org)

Disclaimer

The products and services delivered by the gene editing core is for research purposes only.